Aminoguanidine Protects Against Intracranial Hypertension and Cerebral Ischemic Injury in Experimental Heatstroke

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Aminoguanidine protects against intracranial hypertension and cerebral ischemic injury in experimental heatstroke.

The aim of the present study was to ascertain whether aminoguanidine attenuated intracranial hypertension and cerebral ischemic injury in experimental heatstroke. Urethane-anesthetized rats were exposed to heat stress (ambient temperature of 43 degrees C) to induce heatstroke. Control rats were exposed to 24 degrees C. Mean arterial pressure, cerebral perfusion pressure, and cerebral blood flow...

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ژورنال

عنوان ژورنال: Journal of Pharmacological Sciences

سال: 2004

ISSN: 1347-8613,1347-8648

DOI: 10.1254/jphs.95.56